Muscles and joints shift and jostle. The heart's pounding rhythm speeds up. Blood roars through arteries and veins. Over the course of a pregnancy, every organ in the body changes. Initiated by a range of hormones, these changes begin as soon as a pregnancy begins. Explore what we know— and don't know— about pregnancy's effects on the body and b...

Over-the-counter pregnancy tests give potentially life-changing results with a pretty high rate of accuracy. But how do they work? Tien Nguyen explains how each test performs a scientifically rigorous, multi-stage experiment that goes from start to finish in the time that it’ll take you to watch this video. [Directed by Andrew Foerster, narrated...

In the early 20th century, pregnancy testing required a slippery piece of equipment: a female African clawed frog. For decades, hospitals and research labs had a trusted supply of these handy creatures, employing their help in testing for pregnancy and in numerous other scientific endeavors. So what makes these frogs so special? Carly Anne York ...

Shocking, but true: the United States has the highest rate of deaths for new mothers of any developed country -- and 60 percent of them are preventable. With clarity and urgency, physician Elizabeth Howell explains the causes of maternal mortality and shares ways for hospitals and doctors to make pregnancy safer for women before, during and afte...

Globally, around 23 million pregnancies end in miscarriage each year. Despite how common it is, miscarriage can still feel isolating, and for some, emotionally traumatizing. And myths about miscarriage add to the stigma, leading many to blame themselves for the loss. So what happens in the body during miscarriage? Nassim Assefi & Emily M. Go...

Contraceptives are designed to prevent pregnancy in three basic ways: they either block sperm, disable sperm before they reach the uterus, or suppress ovulation. But is one strategy better than the other? And how does each one work? NWHunter describes the mechanics behind different kinds of contraceptives. [Directed by Draško Ivezić, narrated by...

There's a reliable indicator of a woman's future likelihood of cardiovascular disease — but it rarely gets asked about, says obstetrician and researcher Meryam Sugulle. She delves into the role of the placenta in pregnancy, how it can predict health outcomes and the single question that should be worked into routine health screenings.

"When we tell women that sex isn't worth the risk during pregnancy, what we're telling her is that her sexual pleasure doesn't matter ... that she in fact doesn't matter," says sex researcher Sofia Jawed-Wessel. In this eye-opening talk, Jawed-Wessel mines our views about pregnancy and pleasure to lay bare the relationship between women, sex and...

Zubaida Bai innovates health and livelihood solutions for underserved women and girls around the world.

Andrologist John Amory is developing innovative male contraception that gives men a new option for taking responsibility to prevent unintended pregnancy. He details the science in development -- and why the world needs a male pill.

Twenty-three Grand Slam titles later, tennis superstar Serena Williams sits down with journalist Gayle King to share a warm, mischievous conversation about her life, love, wins and losses -- starting with the story of how she accidentally shared her pregnancy news with the world.

All mammals share certain characteristics, like warm blood and backbones. But despite their similarities, these creatures also have many biological differences — and one of the most remarkable differences is how they give birth. Kate Slabosky details the placental, marsupial, and monotreme methods of giving birth. [Directed by Compote Collective...

Today, there are many ways to conceive a child, thanks to assisted reproductive technologies like IVF and egg-freezing. But the law lags behind these advancements, says attorney Ellen Trachman, troubling parents-to-be with stranger-than-fiction mix-ups and baffling lawsuits. Trachman makes the case for legality to reflect the realities of reprod...

Meryam Sugulle uncovers ways to improve women's future health outcomes.

Seriously, let's talk about sex: 8 insightful talks to spark the conversations we need to have in (and out of) the bedroom.

In the US, Black women are nearly 300 percent more likely to die as a result of childbirth than white women. Sharing appalling statistics on maternal mortality as well as her own tragic story of loss, Wanda Irving explains how racism and bias in health care minimizes and dismisses Black women's pain -- and makes a personal plea for leaders in th...

Diana Greene Foster studies the consequences of unintended pregnancy and access to abortion on people's lives.

Infertility affects 1 in 8 couples worldwide. But in the last 40 years, more than 5 million babies have been born using in vitro fertilization (IVF). How does it work? Nassim Assefi and Brian A. Levine detail the science behind making a baby in a lab.

Your lifelong health may have been decided the day you were born, says microbiome researcher Henna-Maria Uusitupa. In this fascinating talk, she shows how the gut microbes you acquire during birth and as an infant impact your health into adulthood -- and discusses new microbiome research that could help tackle problems like obesity and diabetes.

Annie Murphy Paul investigates how life in the womb shapes who we become.

Pop quiz: When does learning begin? Answer: Before we are born. Science writer Annie Murphy Paul talks through new research that shows how much we learn in the womb -- from the lilt of our native language to our soon-to-be-favorite foods.

Miriam Zoila Pérez investigates how race and gender affect health -- and the people who create spaces for healing.

The midwife Xoquauhtli has a difficult choice to make. She owes a debt to her patron Teteoinnan, the female warrior goddess at the center of the Aztec seasonal festival, who must be kept happy or she will bring bad luck. Xoquauhtli should participate in the festival today, but one of her patients could go into labor any minute. Kay Read outlines...

Robyn Stein DeLuca asks, What do we really know about PMS?

TED Fellow Karen "Kaz" Lucas is a leader in the world of arts and culture in Kenya.

Alexandra Sacks, M.D. is widely recognized as the leading clinical expert on matrescence: the developmental transition into motherhood.

Mark Edwards is the cofounder and CEO of Upstream USA, a nonprofit working to expand contraceptive access in the United States.

Moshe Szyf is a pioneer in the field of epigenetics, the study of how living things reprogram their genome in response to social factors like stress and lack of food. His research suggests that biochemical signals passed from mothers to offspring tell the child what kind of world they're going to live in, changing the expression of genes. "DNA i...

TED Fellow Zubaida Bai works with medical professionals, midwives and mothers to bring dignity and low-cost interventions to women's health care. In this quick, inspiring talk, she presents her clean birth kit in a purse, which contains everything a new mother needs for a hygienic birth and a healthy delivery -- no matter where in the world (or ...

Image-maker Alexander Tsiaras shares a powerful medical visualization, showing human development from conception to birth and beyond. (Some graphic images.)